Decreased IgE-binding with Wheat Gluten by Deamidation.

نویسندگان

  • N Maruyama
  • F Sugiura
  • T Kishimoto
  • K Ichise
  • Y Takeuchi
  • T Sawada
  • A Tsuda
  • S Utsumi
چکیده

The major wheat allergens contain a number of glutamine residues, suggesting that deamidation would be a promising method to produce hypoallergenic wheat proteins. Gluten was deamidated by acid under various conditions. The 30%-, 50%- and 90%-deamidated glutens were reacted with sera of patients allergic to wheat proteins. The results indicate that the reactivity was dramatically decreased according to the degree of deamidation.

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عنوان ژورنال:
  • Bioscience, biotechnology, and biochemistry

دوره 63 3  شماره 

صفحات  -

تاریخ انتشار 1999